CFHR5

Across TCGA patient cohorts, CFHR5 protein abundance is significantly associated with the RNA expression of many other genes, with 11,665 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CFHR5-associated genes across cancer lineages are IL6, FGF7, and PTGIR. Each is linked with CFHR5 in more than 7 cancer types. Because this analysis shows association rather than direction, both CFHR5-to-partner and partner-to-CFHR5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CFHR5 versus IL6 in GBM, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CFHR5→partner) and Y-score (partner→CFHR5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	IL6 →	+1.850	+0.916	<.001	<.001	3	8
OV	FGF7 →	+1.099	+0.520	<.001	<.001	3	8
LUAD	PTGIR →	+0.649	+0.703	<.001	<.001	3	8
COAD	FLT1 →	+0.846	+0.697	<.001	<.001	3	7
OV	SERPINE1 →	+1.461	+0.589	.002	.004	3	7
UCEC	MMP19 →	+0.935	+0.561	<.001	.005	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,665 associations by consensus.

CFHR5 vs IL6 — GBM

Explore this scatter interactively →