CFHR5

Across TCGA cell cohorts, CFHR5 RNA expression is significantly associated with the go_rna of many other GO terms, with 381 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible CFHR5-associated GO terms across cancer lineages are Positive regulation of metanephros development, Regulation of metanephric glomerulus development, and Positive regulation of metanephric glomerulus development. Each is linked with CFHR5 in more than 2 cancer types. Because this analysis shows association rather than direction, both CFHR5-to-partner and partner-to-CFHR5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of metanephros development grouped by CFHR5-low versus CFHR5-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CFHR5→partner) and Y-score (partner→CFHR5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Positive regulation of metanephros development →	+0.918	+0.012	.001	<.001	3	3
BREAST	Regulation of metanephric glomerulus development →	+0.918	+0.012	.001	<.001	3	3
BREAST	Positive regulation of metanephric glomerulus development →	+0.918	+0.012	.001	<.001	3	3
BREAST	Protein activation cascade →	-0.194	-0.012	.007	<.001	3	3
LUNG_NSCLC_LUAD	Heme transport →	+0.090	+0.006	<.001	.002	3	3
LUNG_SCLC	Protein prenylation →	+0.084	+0.034	.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 381 associations by consensus.

Positive regulation of metanephros development by CFHR5 expression — BREAST

Explore this box plot interactively →