CFHR4

Across TCGA patient cohorts, CFHR4 protein abundance is significantly associated with the RNA expression of many other genes, with 10,492 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible CFHR4-associated genes across cancer lineages are MYL3, MEDAG, and SERPINE1. Each is linked with CFHR4 in more than 3 cancer types. Because this analysis shows association rather than direction, both CFHR4-to-partner and partner-to-CFHR4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CFHR4 versus MYL3 in UCEC, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CFHR4→partner) and Y-score (partner→CFHR4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MYL3 →	+0.726	+0.811	.005	.005	3	3
GBM	MEDAG →	+1.117	+0.861	.001	.001	3	3
GBM	SERPINE1 →	+1.249	+0.641	.002	.009	3	3
LUAD	FNDC4 →	+0.846	+0.430	.003	.005	2	4
GBM	RGS2 →	+1.271	+0.987	<.001	<.001	3	3
LSCC	PTGER2 →	+0.655	+0.533	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,492 associations by consensus.

CFHR4 vs MYL3 — UCEC

Explore this scatter interactively →