CFHR4

Across TCGA cell cohorts, CFHR4 RNA expression is significantly associated with the go_rna of many other GO terms, with 517 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible CFHR4-associated GO terms across cancer lineages are Gamma-aminobutyric acid signaling pathway, Connective tissue development, and Regulation of dephosphorylation. Each is linked with CFHR4 in more than 4 cancer types. Because this analysis shows association rather than direction, both CFHR4-to-partner and partner-to-CFHR4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Gamma-aminobutyric acid signaling pathway grouped by CFHR4-low versus CFHR4-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CFHR4→partner) and Y-score (partner→CFHR4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Gamma-aminobutyric acid signaling pathway →	-0.229	-0.099	.005	.009	3	5
CNS	Connective tissue development →	-0.039	-0.124	.003	.006	3	4
BREAST	Regulation of dephosphorylation →	+0.061	+0.081	<.001	.008	3	4
LUNG_SCLC	Regulation of respiratory gaseous exchange →	+0.123	+0.088	.003	.007	3	3
OESOPHAGUS	Activation of meiosis →	+1.042	+0.160	.002	.004	3	3
CNS	Transcription by RNA polymerase I →	+0.053	+0.076	.004	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 517 associations by consensus.

Gamma-aminobutyric acid signaling pathway by CFHR4 expression — STOMACH

Explore this box plot interactively →