CFHR3

Across TCGA pan-cancer cohorts, CFHR3 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated CFHR3 data layer compared with 20 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher CFHR3 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated CFHR3 expression acts as an unfavorable survival marker.

LUAD, CCRCC, and LSCC are the cancer types where CFHR3 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Tertile	III,IV	0.402	0.879	.016	21	view →
CCRCC	DFS	Quartile	II,III,IV	0.393	0.790	.012	17	view →
LSCC	OS	Tertile	All	0.958	1.000	.022	1	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

CFHR3–LUAD (OS)

Open the LUAD breakdown →