CFDP1

Across TCGA patient cohorts, CFDP1 mutation is significantly associated with the total protein of many other genes, with 9 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CFDP1-associated genes across cancer lineages are Ku80, p62 Lck ligand, and AMPK_pT172. Each is linked with CFDP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CFDP1-to-partner and partner-to-CFDP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ku80 grouped by CFDP1-low versus CFDP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CFDP1→partner) and Y-score (partner→CFDP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Ku80 →	+0.312	+3.183	.016	.010	3	1
UCEC	p62 Lck ligand →	+0.502	+3.169	.004	.020	3	1
UCEC	AMPK_pT172 →	+0.471	+3.000	.037	.036	3	1
UCEC	PCNA →	+0.338	+3.000	.004	.036	2	1
UCEC	ERK2 →	+0.230	+3.169	.030	.020	1	1
UCEC	PRDX1 →	+0.341	+3.169	.002	.020	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

Ku80 by CFDP1 expression — UCEC

Explore this box plot interactively →