Across TCGA patient cohorts, CFD RNA expression is significantly associated with the protein abundance of many other proteins, with 16,906 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CFD-associated proteins across cancer lineages are LYVE1, F13A1, and FOLR2. Each is linked with CFD in more than 6 cancer types. Because this analysis shows association rather than direction, both CFD-to-partner and partner-to-CFD results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CFD→partner) and Y-score (partner→CFD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	LYVE1 →	+0.620	+0.900	<.001	<.001	3	7
GBM	F13A1 →	+1.111	+1.130	<.001	<.001	3	7
GBM	FOLR2 →	+1.092	+1.159	<.001	<.001	3	7
BRCA	ALYREF →	-0.340	-1.226	<.001	<.001	3	7
BRCA	SOD3 →	+0.777	+1.258	<.001	<.001	3	6
OV	ANKRD44 →	+0.347	+1.473	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,906 associations by consensus.

Exploration

CFD survival (RNA) · tumor vs normal (RNA) · all CFD data types