Across TCGA patient cohorts, CFD protein abundance is significantly associated with the RNA expression of many other genes, with 13,496 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CFD-associated genes across cancer lineages are C7, CNRIP1, and CDO1. Each is linked with CFD in more than 7 cancer types. Because this analysis shows association rather than direction, both CFD-to-partner and partner-to-CFD results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CFD→partner) and Y-score (partner→CFD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	C7 →	+2.418	+0.503	<.001	<.001	3	8
BRCA	CNRIP1 →	+1.035	+0.788	<.001	<.001	3	8
HNSC	CDO1 →	+1.244	+0.448	<.001	<.001	3	8
BRCA	AOC3 →	+1.658	+0.813	<.001	<.001	3	8
BRCA	JAM3 →	+1.096	+0.776	<.001	<.001	3	8
OV	PODN →	+1.938	+0.655	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,496 associations by consensus.

Exploration

CFD survival (RNA) · tumor vs normal (RNA) · all CFD data types