Across TCGA cell cohorts, CFD mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible CFD-associated genes across cancer lineages are GJA10 and SIGLECL1. Each is linked with CFD in more than 1 cancer types. Because this analysis shows association rather than direction, both CFD-to-partner and partner-to-CFD results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CFD→partner) and Y-score (partner→CFD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	GJA10 →	+0.039	+5.169	<.001	.005	3	1
LARGE_INTESTINE	SIGLECL1 →	+0.022	+4.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Exploration

CFD survival (RNA) · tumor vs normal (RNA) · all CFD data types