CFC1

Across TCGA patient cohorts, CFC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,687 significant associations in total. LGG shows the largest number of these associations.

The most reproducible CFC1-associated GO terms across cancer lineages are Microtubule-based transport, Hematopoietic stem cell homeostasis, and Transport along microtubule. Each is linked with CFC1 in more than 7 cancer types. Because this analysis shows association rather than direction, both CFC1-to-partner and partner-to-CFC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule-based transport grouped by CFC1-low versus CFC1-high in LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CFC1→partner) and Y-score (partner→CFC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	Microtubule-based transport →	+0.027	+0.027	<.001	<.001	3	8
TGCT	Hematopoietic stem cell homeostasis →	+0.058	+0.584	<.001	<.001	3	7
CESC	Transport along microtubule →	+0.029	+0.008	<.001	<.001	3	7
TGCT	Pancreas development →	+0.043	+0.648	<.001	<.001	3	7
CESC	Intraciliary anterograde transport →	+0.057	+0.004	<.001	.003	3	7
TGCT	Negative regulation of Notch signaling pathway →	+0.051	+0.858	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,687 associations by consensus.

Microtubule-based transport by CFC1 expression — LUAD

Explore this box plot interactively →