CFC1

RNA expression — cross-omics
Cross-omicsRNA → DRUGCell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CFC1 RNA expression is significantly associated with the drug of many other genes, with 88 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible CFC1-associated genes across cancer lineages are Zoledronate, Dacarbazine, and N25720-51-A1. Each is linked with CFC1 in more than 2 cancer types. Because this analysis shows association rather than direction, both CFC1-to-partner and partner-to-CFC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Zoledronate grouped by CFC1-low versus CFC1-high in LUNG_NSCLC_LUAD.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CFC1→partner) and Y-score (partner→CFC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_NSCLC_LUADZoledronate →-0.452-0.010.004.02633
LUNG_NSCLC_LUADDacarbazine →-0.652-0.006.001.01933
LUNG_NSCLC_LUADN25720-51-A1 →-0.654-0.007.008.00933
LUNG_NSCLC_LUADGSK-LSD1-2HCl →-0.487-0.007.003.00933
LUNG_NSCLC_LUADCPI-637 →-0.428-0.010.036.03533
LUNG_NSCLC_LUADUNC0379 →-0.607-0.008.004.03233
Each partner links to its Q-omics profile. Showing the 6 strongest of 88 associations by consensus.

Zoledronate by CFC1 expression — LUNG_NSCLC_LUAD

Box plot of Zoledronate in CFC1-low vs CFC1-high samples in LUNG_NSCLC_LUAD.

Explore this box plot interactively →

Exploration