CFAP94

Across TCGA patient cohorts, CFAP94 mutation is significantly associated with the total protein of many other genes, with 31 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CFAP94-associated genes across cancer lineages are JNK_pT183_Y185, N-Ras, and p53. Each is linked with CFAP94 in more than 1 cancer types. Because this analysis shows association rather than direction, both CFAP94-to-partner and partner-to-CFAP94 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, JNK_pT183_Y185 grouped by CFAP94-low versus CFAP94-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CFAP94→partner) and Y-score (partner→CFAP94) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	JNK_pT183_Y185 →	-0.171	-2.222	.002	.010	3	2
UCEC	N-Ras →	-0.082	-1.234	.043	.045	3	2
UCEC	p53 →	-0.336	-1.807	.010	.004	3	2
UCEC	p70-S6K_pT389 →	-0.161	-2.807	.012	.002	3	2
UCEC	Rab25 →	-0.355	-2.137	.001	.001	3	2
UCEC	Annexin_VII →	-0.103	-2.105	.030	.017	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

JNK_pT183_Y185 by CFAP94 expression — UCEC

Explore this box plot interactively →