CFAP94

mutation — cross-omics
Cross-omicsMUTATION → DRUGCell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CFAP94 mutation is significantly associated with the drug of many other genes, with 14 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CFAP94-associated genes across cancer lineages are AZD7969, PLK_6522, and 50869. Each is linked with CFAP94 in more than 1 cancer types. Because this analysis shows association rather than direction, both CFAP94-to-partner and partner-to-CFAP94 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AZD7969 grouped by CFAP94-low versus CFAP94-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CFAP94→partner) and Y-score (partner→CFAP94) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEAZD7969 →+0.506+2.649.026.04631
LARGE_INTESTINEPLK_6522 →+0.668+2.649.043.04631
LARGE_INTESTINE50869 →+0.423+2.649.046.04631
LARGE_INTESTINEIspinesib Mesylate →+0.672+2.652.040.04531
LARGE_INTESTINEGSK429286A →+0.310+2.652.048.04531
LARGE_INTESTINEWZ3105 →+0.884+2.652.009.04531
Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

AZD7969 by CFAP94 expression — LARGE_INTESTINE

Box plot of AZD7969 in CFAP94-low vs CFAP94-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration