CFAP92

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CFAP92 mutation is significantly associated with the RNA expression of many other genes, with 1,532 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CFAP92-associated genes across cancer lineages are ZNHIT3, TAF9, and TUFM. Each is linked with CFAP92 in more than 1 cancer types. Because this analysis shows association rather than direction, both CFAP92-to-partner and partner-to-CFAP92 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZNHIT3 grouped by CFAP92-low versus CFAP92-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CFAP92→partner) and Y-score (partner→CFAP92) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECZNHIT3 →+0.392+2.021.008.00532
UCECTAF9 →+0.708+3.828<.001<.00132
UCECTUFM →+0.359+2.658.008.00532
UCECCYC1 →+0.504+2.939.005<.00132
UCECLSM10 →+0.389+2.831.001.00132
UCECNGRN →+0.629+2.513<.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,532 associations by consensus.

ZNHIT3 by CFAP92 expression — UCEC

Box plot of ZNHIT3 in CFAP92-low vs CFAP92-high samples in UCEC.

Explore this box plot interactively →

Exploration