Across TCGA patient cohorts, CFAP91 mutation is significantly associated with the RNA expression of many other genes, with 5,953 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CFAP91-associated genes across cancer lineages are DTL, MCM10, and RRM2. Each is linked with CFAP91 in more than 4 cancer types. Because this analysis shows association rather than direction, both CFAP91-to-partner and partner-to-CFAP91 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CFAP91→partner) and Y-score (partner→CFAP91) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	DTL →	+0.866	+3.332	<.001	<.001	3	5
UCEC	MCM10 →	+0.789	+1.906	<.001	<.001	3	5
UCEC	RRM2 →	+1.119	+2.146	<.001	<.001	3	5
UCEC	NUSAP1 →	+0.945	+2.415	<.001	<.001	3	5
LUAD	GINS1 →	+0.779	+2.596	.003	.005	3	4
LUAD	PIMREG →	+1.009	+2.918	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,953 associations by consensus.

Exploration

CFAP91 survival (RNA) · tumor vs normal (RNA) · all CFAP91 data types