Across TCGA patient cohorts, CFAP77 mutation is significantly associated with the total protein of many other genes, with 30 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CFAP77-associated genes across cancer lineages are ASNS, PKC-a, and c-Myc. Each is linked with CFAP77 in more than 1 cancer types. Because this analysis shows association rather than direction, both CFAP77-to-partner and partner-to-CFAP77 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CFAP77→partner) and Y-score (partner→CFAP77) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	ASNS →	+0.856	+3.459	<.001	.005	3	2
COAD	PKC-a →	-0.392	-3.000	.004	.035	3	1
COAD	c-Myc →	-0.276	-3.157	.017	.018	3	1
SKCM	HER3_pY1289 →	+0.180	+2.840	<.001	.033	3	1
SKCM	MIG-6 →	+0.216	+3.476	.006	.002	3	1
SKCM	Stathmin →	+0.226	+2.321	.011	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 30 associations by consensus.

Exploration

CFAP77 survival (RNA) · tumor vs normal (RNA) · all CFAP77 data types