CFAP77

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CFAP77 mutation is significantly associated with the RNA expression of many other genes, with 31 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CFAP77-associated genes across cancer lineages are H2BC1, H2AC1, and KRT6C. Each is linked with CFAP77 in more than 1 cancer types. Because this analysis shows association rather than direction, both CFAP77-to-partner and partner-to-CFAP77 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CFAP77→partner) and Y-score (partner→CFAP77) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SOFT_TISSUEH2BC1 →+0.433+5.977<.001.00131
SOFT_TISSUEH2AC1 →+0.193+5.977<.001.00131
SOFT_TISSUEKRT6C →+0.013+4.930<.001.00831
SOFT_TISSUEKRTAP10-1 →+0.034+5.369.002.00431
SOFT_TISSUEGAGE12E →+0.090+4.930<.001.00831
SOFT_TISSUEIFNA14 →+0.032+5.369<.001.00431
Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

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