CFAP65

Across TCGA pan-cancer cohorts, CFAP65 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated CFAP65 data layer compared with 22 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher CFAP65 Mutation is associated with better overall survival. In most high-consensus cancer types, elevated CFAP65 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

UCEC, ESCA, and BLCA are the cancer types where CFAP65 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	II,III,IV	0.866	0.451	.016	18	view →
ESCA	OS	Median	III,IV	0.108	0.574	<.001	12	view →
BLCA	OS	Median	All	0.174	0.592	.030	6	view →
SKCM	DFS	Median	All	0.108	0.215	.038	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

CFAP65–UCEC (OS)

Open the UCEC breakdown →