CFAP65

Across TCGA patient cohorts, CFAP65 mutation is significantly associated with the RNA expression of many other genes, with 8,582 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CFAP65-associated genes across cancer lineages are MEX3D, BMS1P20, and PGAM5. Each is linked with CFAP65 in more than 4 cancer types. Because this analysis shows association rather than direction, both CFAP65-to-partner and partner-to-CFAP65 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MEX3D grouped by CFAP65-low versus CFAP65-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CFAP65→partner) and Y-score (partner→CFAP65) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MEX3D →	+0.520	+1.480	<.001	<.001	3	5
UCEC	BMS1P20 →	+0.266	+1.233	.002	<.001	3	5
UCEC	PGAM5 →	+0.498	+1.716	<.001	<.001	3	5
UCEC	OIP5 →	+0.794	+2.176	<.001	<.001	3	5
UCEC	PIMREG →	+0.657	+1.875	<.001	<.001	3	5
UCEC	CDCA5 →	+0.638	+2.010	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,582 associations by consensus.

MEX3D by CFAP65 expression — UCEC

Explore this box plot interactively →