CFAP65

Across TCGA patient cohorts, CFAP65 mutation is significantly associated with the total protein of many other genes, with 72 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CFAP65-associated genes across cancer lineages are eIF4E, Caspase-7-cleavedD198, and Cyclin-B1. Each is linked with CFAP65 in more than 3 cancer types. Because this analysis shows association rather than direction, both CFAP65-to-partner and partner-to-CFAP65 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eIF4E grouped by CFAP65-low versus CFAP65-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CFAP65→partner) and Y-score (partner→CFAP65) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	eIF4E →	+0.220	+3.000	.011	.033	3	4
COAD	Caspase-7-cleavedD198 →	+1.145	+3.700	<.001	.001	3	4
UCEC	Cyclin-B1 →	+0.499	+2.201	<.001	<.001	3	4
LUAD	PKC-delta_pS664 →	-0.117	-3.169	.029	.018	3	3
STAD	4E-BP1 →	+0.381	+3.169	.009	.019	3	3
BRCA	PAI-1 →	+0.527	+2.814	.021	.037	2	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 72 associations by consensus.

eIF4E by CFAP65 expression — CESC

Explore this box plot interactively →