CFAP58

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CFAP58 protein abundance is significantly associated with the RNA expression of many other genes, with 1,486 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CFAP58-associated genes across cancer lineages are PPIL6, VNN3, and SPEF1. Each is linked with CFAP58 in more than 2 cancer types. Because this analysis shows association rather than direction, both CFAP58-to-partner and partner-to-CFAP58 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CFAP58 versus PPIL6 in UCEC, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CFAP58→partner) and Y-score (partner→CFAP58) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECPPIL6 →+1.400+0.918.007.00633
UCECVNN3 →+1.340+1.086<.001<.00133
LSCCSPEF1 →+0.909+0.951.001.00232
LSCCRP1 →+1.309+1.047<.001<.00132
LUADCAPS →+1.030+0.722.001.00532
LSCCRSPH4A →+0.974+0.664.002.00632
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,486 associations by consensus.

CFAP58 vs PPIL6 — UCEC

Per-sample scatter of CFAP58 vs PPIL6 in UCEC (Pearson r = 0.37).

Explore this scatter interactively →

Exploration