CFAP58

Across TCGA cell cohorts, CFAP58 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,336 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CFAP58-associated GO terms across cancer lineages are Regulation of focal adhesion assembly, Regulation of cell-substrate junction assembly, and Hemostasis. Each is linked with CFAP58 in more than 7 cancer types. Because this analysis shows association rather than direction, both CFAP58-to-partner and partner-to-CFAP58 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of focal adhesion assembly grouped by CFAP58-low versus CFAP58-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CFAP58→partner) and Y-score (partner→CFAP58) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Regulation of focal adhesion assembly →	+0.095	+0.261	.006	.002	3	8
LUNG_NSCLC_LUSC	Regulation of cell-substrate junction assembly →	+0.095	+0.261	.006	.002	3	8
SOFT_TISSUE	Hemostasis →	+0.081	+0.499	<.001	<.001	3	7
SKIN	Integrin-mediated signaling pathway →	+0.135	+0.376	<.001	.005	3	7
CNS	Sperm mitochondrial sheath assembly →	-0.151	-0.407	<.001	<.001	3	7
LUNG_NSCLC_LUSC	Positive regulation of cell-substrate junction organization →	+0.153	+0.324	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,336 associations by consensus.

Regulation of focal adhesion assembly by CFAP58 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →