Across TCGA patient cohorts, CFAP45 mutation is significantly associated with the RNA expression of many other genes, with 3,909 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CFAP45-associated genes across cancer lineages are DTL, PBK, and ELAC2. Each is linked with CFAP45 in more than 3 cancer types. Because this analysis shows association rather than direction, both CFAP45-to-partner and partner-to-CFAP45 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CFAP45→partner) and Y-score (partner→CFAP45) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	DTL →	+0.533	+2.217	.001	<.001	3	4
UCEC	PBK →	+0.691	+1.698	.001	<.001	3	4
UCEC	ELAC2 →	+0.429	+2.769	<.001	<.001	3	4
SKCM	E2F7 →	+0.517	+3.385	.007	.004	3	3
UCEC	VDAC1 →	+0.420	+1.730	<.001	<.001	3	3
SKCM	BIRC5 →	+0.618	+2.916	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,909 associations by consensus.

Exploration

CFAP45 survival (RNA) · tumor vs normal (RNA) · all CFAP45 data types