CFAP44

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CFAP44 mutation is significantly associated with the total protein of many other genes, with 56 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CFAP44-associated genes across cancer lineages are eEF2, GAPDH, and PDCD4. Each is linked with CFAP44 in more than 3 cancer types. Because this analysis shows association rather than direction, both CFAP44-to-partner and partner-to-CFAP44 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CFAP44→partner) and Y-score (partner→CFAP44) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECeEF2 →+0.310+1.273.002.00733
UCECGAPDH →+0.380+1.523.011.00633
UCECPDCD4 →-0.339-1.362.010.03133
UCECSTAT3_pY705 →-0.309-1.311<.001.01033
UCECBak →+0.195+1.847.005.00733
UCECEGFR_pY1068 →-0.235-1.632<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 56 associations by consensus.

Exploration