Across TCGA patient cohorts, CFAP43 mutation is significantly associated with the RNA expression of many other genes, with 4,635 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CFAP43-associated genes across cancer lineages are PPP2R2D, BNIP3, and DYNC2I2. Each is linked with CFAP43 in more than 3 cancer types. Because this analysis shows association rather than direction, both CFAP43-to-partner and partner-to-CFAP43 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CFAP43→partner) and Y-score (partner→CFAP43) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PPP2R2D →	+0.232	+2.200	<.001	<.001	3	4
UCEC	BNIP3 →	+0.775	+1.621	<.001	<.001	3	4
UCEC	DYNC2I2 →	+0.379	+2.413	.001	<.001	3	4
UCEC	KIFBP →	+0.456	+1.804	<.001	<.001	3	4
UCEC	TAF9 →	+0.593	+2.104	<.001	<.001	3	3
SKCM	RIPK3 →	-0.545	-1.467	.001	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,635 associations by consensus.

Exploration

CFAP43 survival (RNA) · tumor vs normal (RNA) · all CFAP43 data types