CFAP43

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CFAP43 mutation is significantly associated with the total protein of many other genes, with 49 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CFAP43-associated genes across cancer lineages are ATM, YAP, and INPP4B. Each is linked with CFAP43 in more than 2 cancer types. Because this analysis shows association rather than direction, both CFAP43-to-partner and partner-to-CFAP43 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CFAP43→partner) and Y-score (partner→CFAP43) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECATM →-0.479-2.000<.001<.00133
LUADYAP →+0.374+2.819.002.03523
UCECINPP4B →-0.232-1.807.009.00332
UCECMEK1 →+0.395+1.917<.001<.00132
UCECNotch1 →+0.150+1.653<.001.00132
UCECPCNA →+0.198+1.722<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 49 associations by consensus.

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