CFAP300

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CFAP300 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,875 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CFAP300-associated GO terms across cancer lineages are Regulation of protein monoubiquitination, Positive regulation of protein monoubiquitination, and Protein localization to ciliary transition zone. Each is linked with CFAP300 in more than 10 cancer types. Because this analysis shows association rather than direction, both CFAP300-to-partner and partner-to-CFAP300 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein monoubiquitination grouped by CFAP300-low versus CFAP300-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CFAP300→partner) and Y-score (partner→CFAP300) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_NSCLC_LUSCRegulation of protein monoubiquitination →+0.165+1.607<.001<.001310
LUNG_NSCLC_LUSCPositive regulation of protein monoubiquitination →+0.165+1.607<.001<.001310
CNSProtein localization to ciliary transition zone →+0.059+1.366.001.001211
STOMACHGolgi to plasma membrane protein transport →+0.091+1.487<.001.001310
SOFT_TISSUEMaintenance of protein location →+0.092+1.094<.001<.00139
SOFT_TISSUEMaintenance of location →+0.084+1.502<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,875 associations by consensus.

Regulation of protein monoubiquitination by CFAP300 expression — LUNG_NSCLC_LUSC

Box plot of Regulation of protein monoubiquitination in CFAP300-low vs CFAP300-high samples in LUNG_NSCLC_LUSC.

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Exploration