CFAP298

Across TCGA pan-cancer cohorts, CFAP298 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated CFAP298 data layer compared with 23 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher CFAP298 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated CFAP298 expression acts as an unfavorable survival marker, although some lineages such as LSCC and LUAD show a favorable association.

CCRCC, HNSC, and LSCC are the cancer types where CFAP298 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	II,III,IV	0.370	0.791	<.001	43	view →
HNSC	OS	Quartile	II,III,IV	0.578	0.858	.005	18	view →
LSCC	OS	Quartile	II,III,IV	1.000	0.617	.003	4	view →
LUAD	DFS	Tertile	III,IV	0.933	0.510	.032	3	view →
PDAC	OS	Quartile	III,IV	1.000	0.594	.045	2	view →
GBM	OS	Quartile	All	0.550	0.931	.009	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

CFAP298–CCRCC (DFS)

Open the CCRCC breakdown →