CFAP298

Across TCGA patient cohorts, CFAP298 mutation is significantly associated with the RNA expression of many other genes, with 839 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CFAP298-associated genes across cancer lineages are RPL23AP4, FCGR1A, and EOMES. Each is linked with CFAP298 in more than 1 cancer types. Because this analysis shows association rather than direction, both CFAP298-to-partner and partner-to-CFAP298 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPL23AP4 grouped by CFAP298-low versus CFAP298-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CFAP298→partner) and Y-score (partner→CFAP298) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RPL23AP4 →	+0.091	+2.861	.003	.009	3	2
UCEC	FCGR1A →	+0.566	+2.087	.004	.006	3	2
UCEC	EOMES →	+0.590	+2.595	<.001	.005	3	2
UCEC	SAP30 →	+0.582	+3.721	.002	<.001	3	2
UCEC	C18orf32 →	+0.343	+3.362	.002	.005	3	2
UCEC	RAD51 →	+0.746	+2.595	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 839 associations by consensus.

RPL23AP4 by CFAP298 expression — COAD

Explore this box plot interactively →