CFAP251

Across TCGA patient cohorts, CFAP251 protein abundance is significantly associated with the RNA expression of many other genes, with 1,897 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible CFAP251-associated genes across cancer lineages are RFC3, MMS22L, and SMIM14. Each is linked with CFAP251 in more than 1 cancer types. Because this analysis shows association rather than direction, both CFAP251-to-partner and partner-to-CFAP251 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CFAP251 versus RFC3 in LUAD, with a Pearson correlation of -0.58.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CFAP251→partner) and Y-score (partner→CFAP251) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RFC3 →	-0.711	-1.036	<.001	<.001	3	2
LUAD	MMS22L →	-0.690	-1.134	<.001	<.001	3	2
UCEC	SMIM14 →	+0.767	+0.798	.002	.004	3	2
UCEC	RRAD →	+2.883	+0.879	<.001	<.001	3	2
UCEC	SCNN1B →	+2.100	+0.768	<.001	.006	3	2
LUAD	ESCO2 →	-0.947	-1.165	.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,897 associations by consensus.

CFAP251 vs RFC3 — LUAD

Explore this scatter interactively →