CFAP221

Across TCGA cell cohorts, CFAP221 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,500 significant associations in total. CNS shows the largest number of these associations.

The most reproducible CFAP221-associated GO terms across cancer lineages are ATP biosynthetic process, Phospholipid biosynthetic process, and Vesicle tethering. Each is linked with CFAP221 in more than 7 cancer types. Because this analysis shows association rather than direction, both CFAP221-to-partner and partner-to-CFAP221 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATP biosynthetic process grouped by CFAP221-low versus CFAP221-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CFAP221→partner) and Y-score (partner→CFAP221) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	ATP biosynthetic process →	+0.111	+0.855	<.001	.001	3	8
UPPER_AERODIGESTIVE_TRACT	Phospholipid biosynthetic process →	+0.054	+0.123	<.001	.001	3	8
SOFT_TISSUE	Vesicle tethering →	+0.050	+0.618	.004	.001	3	8
OVARY	Positive regulation of cation transmembrane transport →	-0.087	-0.425	<.001	.004	3	8
BREAST	ATP synthesis coupled electron transport →	+0.096	+0.603	<.001	.006	3	8
BREAST	Mitochondrial ATP synthesis coupled electron transport →	+0.096	+0.603	<.001	.006	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,500 associations by consensus.

ATP biosynthetic process by CFAP221 expression — BREAST

Explore this box plot interactively →