CFAP20DC

Across TCGA cell cohorts, CFAP20DC mutation is significantly associated with the RNA expression of many other genes, with 432 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CFAP20DC-associated genes across cancer lineages are DEFA4, TEX50, and PATZ1. Each is linked with CFAP20DC in more than 1 cancer types. Because this analysis shows association rather than direction, both CFAP20DC-to-partner and partner-to-CFAP20DC results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DEFA4 grouped by CFAP20DC-low versus CFAP20DC-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CFAP20DC→partner) and Y-score (partner→CFAP20DC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	DEFA4 →	+0.053	+5.807	<.001	.001	3	2
BLOOD_Lymphoma	TEX50 →	+0.056	+5.643	<.001	.002	3	1
LARGE_INTESTINE	PATZ1 →	+0.601	+3.212	.003	.006	3	1
LARGE_INTESTINE	MIOX →	+0.431	+3.410	<.001	.002	3	1
LARGE_INTESTINE	L3MBTL2 →	+0.622	+3.212	.003	.006	3	1
LARGE_INTESTINE	SRP54 →	+0.431	+3.082	.005	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 432 associations by consensus.

DEFA4 by CFAP20DC expression — OVARY

Explore this box plot interactively →