CFAP206

Across TCGA patient cohorts, CFAP206 mutation is significantly associated with the total protein of many other genes, with 40 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CFAP206-associated genes across cancer lineages are Caspase-7-cleavedD198, eEF2, and EGFR_pY1068. Each is linked with CFAP206 in more than 2 cancer types. Because this analysis shows association rather than direction, both CFAP206-to-partner and partner-to-CFAP206 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-7-cleavedD198 grouped by CFAP206-low versus CFAP206-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CFAP206→partner) and Y-score (partner→CFAP206) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-7-cleavedD198 →	+0.752	+2.107	<.001	.002	3	3
UCEC	eEF2 →	+0.294	+3.169	.017	.018	3	2
UCEC	EGFR_pY1068 →	-0.306	-2.070	<.001	.001	3	2
UCEC	INPP4B →	-0.231	-2.415	.039	.002	3	2
UCEC	MEK1 →	+0.560	+2.938	<.001	<.001	3	2
UCEC	Notch1 →	+0.167	+2.070	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 40 associations by consensus.

Caspase-7-cleavedD198 by CFAP206 expression — UCEC

Explore this box plot interactively →