CFAP161

Across TCGA patient cohorts, CFAP161 mutation is significantly associated with the RNA expression of many other genes, with 468 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CFAP161-associated genes across cancer lineages are MIR1269B, BNIP3P23, and CCL5. Each is linked with CFAP161 in more than 1 cancer types. Because this analysis shows association rather than direction, both CFAP161-to-partner and partner-to-CFAP161 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR1269B grouped by CFAP161-low versus CFAP161-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CFAP161→partner) and Y-score (partner→CFAP161) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	MIR1269B →	+0.540	+6.814	<.001	<.001	3	2
BLCA	BNIP3P23 →	+0.092	+5.038	.002	.009	3	1
UCEC	CCL5 →	+1.277	+2.523	<.001	.001	3	1
UCEC	PLS3-AS1 →	+0.213	+3.025	.005	<.001	3	1
UCEC	MIR98 →	+0.329	+2.579	<.001	.001	3	1
UCEC	MIR8071-1 →	+0.906	+1.937	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 468 associations by consensus.

MIR1269B by CFAP161 expression — BLCA

Explore this box plot interactively →