CFAP161

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CFAP161 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CFAP161-associated genes across cancer lineages are OR1L4, OR4D6, and OR51L1. Each is linked with CFAP161 in more than 1 cancer types. Because this analysis shows association rather than direction, both CFAP161-to-partner and partner-to-CFAP161 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR1L4 grouped by CFAP161-low versus CFAP161-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CFAP161→partner) and Y-score (partner→CFAP161) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SOFT_TISSUEOR1L4 →+0.072+5.369<.001.00431
SOFT_TISSUEOR4D6 →+0.046+5.977<.001.00131
SOFT_TISSUEOR51L1 →+0.036+5.369<.001.00431
SOFT_TISSUEOR51G2 →+0.036+5.369<.001.00431
SOFT_TISSUEOR51A4 →+0.006+4.930<.001.00831
SOFT_TISSUEOR6V1 →+0.069+5.369<.001.00431
Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

OR1L4 by CFAP161 expression — SOFT_TISSUE

Box plot of OR1L4 in CFAP161-low vs CFAP161-high samples in SOFT_TISSUE.

Explore this box plot interactively →

Exploration