CFAP100

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CFAP100 mutation is significantly associated with the RNA expression of many other genes, with 4,904 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CFAP100-associated genes across cancer lineages are TUBGCP5, PSMD9, and MRPS15. Each is linked with CFAP100 in more than 2 cancer types. Because this analysis shows association rather than direction, both CFAP100-to-partner and partner-to-CFAP100 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TUBGCP5 grouped by CFAP100-low versus CFAP100-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CFAP100→partner) and Y-score (partner→CFAP100) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECTUBGCP5 →+0.427+2.202<.001<.00133
UCECPSMD9 →+0.423+1.893<.001<.00133
UCECMRPS15 →+0.371+2.627<.001<.00133
UCECSDHB →+0.471+2.169<.001<.00133
UCECNDUFB3 →+0.323+2.471.007.00133
SKCMITGB1BP1 →+0.515+2.360<.001.00233
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,904 associations by consensus.

TUBGCP5 by CFAP100 expression — UCEC

Box plot of TUBGCP5 in CFAP100-low vs CFAP100-high samples in UCEC.

Explore this box plot interactively →

Exploration