CFAP100

Across TCGA patient cohorts, CFAP100 mutation is significantly associated with the total protein of many other genes, with 58 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CFAP100-associated genes across cancer lineages are S6_pS240_S244, ATM, and PCNA. Each is linked with CFAP100 in more than 2 cancer types. Because this analysis shows association rather than direction, both CFAP100-to-partner and partner-to-CFAP100 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, S6_pS240_S244 grouped by CFAP100-low versus CFAP100-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CFAP100→partner) and Y-score (partner→CFAP100) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	S6_pS240_S244 →	+0.442	+3.012	.013	.018	3	3
UCEC	ATM →	-0.597	-3.893	<.001	<.001	3	3
COAD	PCNA →	+0.329	+3.467	.003	.002	3	2
COAD	Rad50 →	-0.265	-3.144	.015	.018	3	2
COAD	ASNS →	+0.569	+2.330	.001	.020	3	2
COAD	Caspase-7-cleavedD198 →	+1.504	+3.467	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 58 associations by consensus.

S6_pS240_S244 by CFAP100 expression — COAD

Explore this box plot interactively →