CFAP100

Across TCGA cell cohorts, CFAP100 mutation is significantly associated with the RNA expression of many other genes, with 21 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CFAP100-associated genes across cancer lineages are DEFA3, SCGB1D4, and TBX5. Each is linked with CFAP100 in more than 1 cancer types. Because this analysis shows association rather than direction, both CFAP100-to-partner and partner-to-CFAP100 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DEFA3 grouped by CFAP100-low versus CFAP100-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CFAP100→partner) and Y-score (partner→CFAP100) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	DEFA3 →	+0.101	+3.887	<.001	.002	3	2
OVARY	SCGB1D4 →	+0.078	+4.222	<.001	.006	3	1
OVARY	TBX5 →	+0.169	+4.095	<.001	.003	3	1
LUNG_SCLC	LYZL2 →	+0.020	+4.643	<.001	.004	3	1
LUNG_SCLC	OR5M11 →	+0.088	+4.269	<.001	.005	3	1
LUNG_SCLC	OR1D5 →	+0.025	+4.643	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

DEFA3 by CFAP100 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →