CETP

Across TCGA pan-cancer cohorts, CETP Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated CETP data layer compared with 25 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in thyroid carcinoma (THCA), where higher CETP Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated CETP expression acts as an unfavorable survival marker, although some lineages such as BLCA show a favorable association.

THCA, SKCM, and BLCA are the cancer types where CETP Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	OS	Median	All	0.277	0.954	<.001	6	view →
SKCM	DFS	Median	II,III,IV	0.051	0.714	<.001	6	view →
BLCA	OS	Median	II,III,IV	1.000	0.410	.047	2	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

CETP–THCA (OS)

Open the THCA breakdown →