CETP

Across TCGA pan-cancer cohorts, CETP mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated CETP data layer compared with 25 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher CETP mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated CETP expression acts as an unfavorable survival marker, although some lineages such as HNSC and PDAC show a favorable association.

HNSC, CCRCC, and PDAC are the cancer types where CETP mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Quartile	All	0.982	0.779	.009	18	view →
CCRCC	DFS	Median	II,III,IV	0.295	0.827	.010	12	view →
PDAC	OS	Quartile	All	0.900	0.376	.024	9	view →
GBM	OS	Median	All	0.421	0.659	.031	2	view →
LUAD	OS	Quartile	II,III,IV	0.224	0.866	.033	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

CETP–HNSC (OS)

Open the HNSC breakdown →