CETP

Across TCGA patient cohorts, CETP protein abundance is significantly associated with the RNA expression of many other genes, with 13,257 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CETP-associated genes across cancer lineages are DIPK2B, CXCR2, and SEMA6B. Each is linked with CETP in more than 4 cancer types. Because this analysis shows association rather than direction, both CETP-to-partner and partner-to-CETP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CETP versus DIPK2B in UCEC, with a Pearson correlation of 0.63.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CETP→partner) and Y-score (partner→CETP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	DIPK2B →	+0.897	+0.470	.002	.001	3	4
GBM	CXCR2 →	+0.843	+0.668	<.001	<.001	3	4
BRCA	SEMA6B →	+0.658	+0.470	.002	.003	2	5
OV	DTX1 →	+1.092	+0.519	.003	.004	3	3
UCEC	HSPA12B →	+0.812	+0.458	.001	.001	3	3
UCEC	MAML2 →	+0.938	+0.564	.002	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,257 associations by consensus.

CETP vs DIPK2B — UCEC

Explore this scatter interactively →