CETN3

Across TCGA patient cohorts, CETN3 mutation is significantly associated with the RNA expression of many other genes, with 858 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CETN3-associated genes across cancer lineages are SNX3P1Y, SEPTIN14P19, and PGAP2. Each is linked with CETN3 in more than 1 cancer types. Because this analysis shows association rather than direction, both CETN3-to-partner and partner-to-CETN3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNX3P1Y grouped by CETN3-low versus CETN3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CETN3→partner) and Y-score (partner→CETN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SNX3P1Y →	+0.093	+4.390	<.001	.003	3	2
HNSC	SEPTIN14P19 →	+0.076	+5.822	<.001	.003	3	1
UCEC	PGAP2 →	+0.395	+3.098	.006	<.001	3	1
UCEC	EI24 →	+0.444	+3.459	.008	.005	3	1
UCEC	FCGR1A →	+0.729	+2.831	<.001	.001	3	1
UCEC	MAT1A →	-0.985	-2.415	.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 858 associations by consensus.

SNX3P1Y by CETN3 expression — UCEC

Explore this box plot interactively →