CETN3

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CETN3 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CETN3-associated genes across cancer lineages are LHCGR and MMP26. Each is linked with CETN3 in more than 1 cancer types. Because this analysis shows association rather than direction, both CETN3-to-partner and partner-to-CETN3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LHCGR grouped by CETN3-low versus CETN3-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CETN3→partner) and Y-score (partner→CETN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINELHCGR →+0.050+4.467<.001.00431
LARGE_INTESTINEMMP26 →+0.060+5.217<.001<.00131
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

LHCGR by CETN3 expression — LARGE_INTESTINE

Box plot of LHCGR in CETN3-low vs CETN3-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration