CETN3

Across TCGA cell cohorts, CETN3 mutation is significantly associated with the mutation status of many other genes, with 645 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CETN3-associated genes across cancer lineages are TIGD4, SGK1, and RAB22A. Each is linked with CETN3 in more than 1 cancer types. Because this analysis shows association rather than direction, both CETN3-to-partner and partner-to-CETN3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TIGD4 grouped by CETN3-low versus CETN3-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CETN3→partner) and Y-score (partner→CETN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TIGD4 →	+3.672	+4.799	.002	.002	1	2
LARGE_INTESTINE	SGK1 →	+3.350	+4.584	.003	.003	1	2
LARGE_INTESTINE	RAB22A →	+5.087	+4.523	.006	.006	1	2
LARGE_INTESTINE	OTOR →	+5.087	+4.523	.006	.006	1	2
LARGE_INTESTINE	FBXL12 →	+4.672	+5.329	<.001	<.001	1	2
LARGE_INTESTINE	RPP38 →	+5.087	+4.523	.006	.006	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 645 associations by consensus.

TIGD4 by CETN3 expression — LARGE_INTESTINE

Explore this box plot interactively →