CETN1

Across TCGA pan-cancer cohorts, CETN1 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated CETN1 data layer compared with 14 for mass-spec protein.

The strongest signal is observed in small cell lung cancer (SCLC), where higher CETN1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated CETN1 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

SCLC, BLCA, and SKCM are the cancer types where CETN1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SCLC	OS	Median	All	0.082	0.708	<.001	36	view →
BLCA	OS	Median	All	0.193	0.720	.002	21	view →
SKCM	DFS	Median	II,III,IV	0.192	0.707	.046	3	view →
UCEC	DFS	Median	II,III,IV	0.846	0.306	.045	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

CETN1–SCLC (OS)

Open the SCLC breakdown →