Across TCGA pan-cancer cohorts, CES5AP1 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated CES5AP1 data layer compared with 1 for mutation status.
The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher CES5AP1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated CES5AP1 expression acts as an unfavorable survival marker, although some lineages such as LAML and LIHC show a favorable association.
CESC, KIRC, and UCEC are the cancer types where CES5AP1 RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.