CES5A

Across TCGA patient cohorts, CES5A RNA expression is significantly associated with the protein abundance of many other proteins, with 8,962 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CES5A-associated proteins across cancer lineages are CACNA1B_S923, CDR2_S311, and FXYD1_S82. Each is linked with CES5A in more than 1 cancer types. Because this analysis shows association rather than direction, both CES5A-to-partner and partner-to-CES5A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CES5A versus CACNA1B_S923 in GBM, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CES5A→partner) and Y-score (partner→CES5A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CACNA1B_S923 →	+1.463	+0.200	<.001	<.001	3	2
GBM	CDR2_S311 →	-0.712	-0.266	<.001	.005	3	2
GBM	FXYD1_S82 →	+0.551	+0.155	.002	.004	3	2
COAD	HACE1 →	+0.746	+0.056	.002	.009	3	2
HNSC	NACC1 →	-0.171	-0.288	.005	.002	3	2
GBM	PFKFB2 →	+0.534	+0.193	.002	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,962 associations by consensus.

CES5A vs CACNA1B_S923 — GBM

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