CES3

Across TCGA patient cohorts, CES3 protein abundance is significantly associated with the RNA expression of many other genes, with 3,801 significant associations in total. COAD shows the largest number of these associations.

The most reproducible CES3-associated genes across cancer lineages are SELENBP1, GJB1, and ZMYND12. Each is linked with CES3 in more than 2 cancer types. Because this analysis shows association rather than direction, both CES3-to-partner and partner-to-CES3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CES3 versus SELENBP1 in LSCC, with a Pearson correlation of 0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CES3→partner) and Y-score (partner→CES3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SELENBP1 →	+1.886	+0.724	<.001	.002	3	3
BRCA	GJB1 →	+1.665	+0.911	.006	<.001	3	3
CCRCC	ZMYND12 →	+0.685	+0.543	.001	.001	3	3
HNSC	TSPY26P →	-0.936	-0.794	.001	<.001	3	3
LSCC	PIGR →	+3.121	+0.782	<.001	<.001	3	3
CCRCC	RNF183 →	+0.926	+0.546	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,801 associations by consensus.

CES3 vs SELENBP1 — LSCC

Explore this scatter interactively →