CES2

Across TCGA patient cohorts, CES2 protein abundance is significantly associated with the RNA expression of many other genes, with 9,726 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible CES2-associated genes across cancer lineages are RRAD, BLCAP, and PTK6. Each is linked with CES2 in more than 5 cancer types. Because this analysis shows association rather than direction, both CES2-to-partner and partner-to-CES2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CES2 versus RRAD in UCEC, with a Pearson correlation of 0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CES2→partner) and Y-score (partner→CES2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RRAD →	+2.054	+0.652	<.001	<.001	3	6
UCEC	BLCAP →	+0.452	+0.609	.004	.001	3	5
LSCC	PTK6 →	+1.051	+0.806	<.001	<.001	3	4
LSCC	PI3 →	+2.537	+0.933	<.001	<.001	3	4
CCRCC	HNF4A →	+1.335	+0.532	<.001	<.001	3	4
BRCA	DOK4 →	+0.524	+0.356	.002	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,726 associations by consensus.

CES2 vs RRAD — UCEC

Explore this scatter interactively →