CES2

Across TCGA cell cohorts, CES2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,874 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CES2-associated GO terms across cancer lineages are Vesicle uncoating, Positive regulation of intracellular steroid hormone receptor signaling pathway, and Alkaloid catabolic process. Each is linked with CES2 in more than 12 cancer types. Because this analysis shows association rather than direction, both CES2-to-partner and partner-to-CES2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vesicle uncoating grouped by CES2-low versus CES2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CES2→partner) and Y-score (partner→CES2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Vesicle uncoating →	+0.125	+0.828	<.001	<.001	3	13
URINARY_TRACT	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.207	+1.199	<.001	<.001	3	13
LUNG_SCLC	Alkaloid catabolic process →	+1.014	+0.784	<.001	<.001	3	13
SOFT_TISSUE	Cytosolic transport →	+0.055	+0.804	<.001	<.001	3	12
BREAST	Vacuolar transport →	+0.061	+1.035	<.001	<.001	3	12
OVARY	Positive regulation of transforming growth factor beta receptor signaling pathway →	+0.126	+1.386	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,874 associations by consensus.

Vesicle uncoating by CES2 expression — BONE

Explore this box plot interactively →